аутоцитофагия
English translation: autophagy (autophagocytosis)
| 13:57 Feb 25, 2021 |
| Russian to English translations [PRO] Medical - Medical (general) | |||||||
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|  Selected response from: Marlin31 Russian Federation Local time: 16:02 | ||||||
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18 mins confidence: 
peer agreement (net): +1
peer agreement (net): +1autophagy (autophagocytosis) Explanation: I think they mean autophagocytosis (autophagy) https://www.tebu-bio.com/blog/tag/autophagocytosis/ Autophagy (Autophagocytosis) describes the fundamental catabolic mechanism during which cells degrade dysfunctional and unnecessary cellular components. This process is driven by the action of lysosomes and promotes survival during starvation periods as the cellular energy level can thus be maintained. https://en.wikipedia.org/wiki/Autophagy Autophagy (or autophagocytosis) (from the Ancient Greek αὐτόφαγος autóphagos, meaning "self-devouring"[1] and κύτος kýtos, meaning "hollow"[2]) is the natural, regulated mechanism of the cell that removes unnecessary or dysfunctional components.[3] It allows the orderly degradation and recycling of cellular components.[4][5] Although initially characterised as a primordial degradation pathway induced to protect against starvation, it has become increasingly clear that autophagy also plays a major role in the homeostasis of non-starved cells. -------------------------------------------------- Note added at 20 мин (2021-02-25 14:18:07 GMT) -------------------------------------------------- https://sci-news.ru/2019/autofagija/ Аутофагия (или аутофагоцитоз) — это адаптационный механизм клетки, позволяющий переваривать собственные компоненты, чтобы повторно использовать их материал. |
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45 mins confidence:
Natural killer (NK) Cell Autoreactivity/Autoreactive cytotoxic T cells Explanation: Феномен аутоцитофагии (вторичный гемофагоцитарный лимфогистиоцитоз). https://vk.com/@provrach-rss-327570472-686884980 The clinical manifestation of moderate to severe coronavirus disease 2019 (COVID-19) has parallels to secondary hemophagocytic lymphohistiocytosis (HLH) both clinically and based on molecular inflammatory response. https://academic.oup.com/cid/advance-article/doi/10.1093/cid... HLH can be categorized into primary and secondary HLH. The former category encapsulates five genetic forms of HLH, which include mutations in Perforin-1, UNC13D, STX11, and STXBP2 proteins [2]. Mutation in the aforementioned proteins leads to impaired natural killer (NK) cell or cytotoxic T-cell activity due to ineffective perforin function or ineffective trafficking, docking and exocytosis of perforin-containing granules. As a result of impaired killing function, NK and cytotoxic T-cells excessively release cytokines and cause immune hyperactivation [2]. https://www.hindawi.com/journals/cricc/2019/3580796/ NK cell autoreactivity and autoimmune diseases https://www.frontiersin.org/articles/10.3389/fimmu.2014.0002... |
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1 day 2 hrs confidence:
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